ODCs

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2 OMIM references -
1 associated gene
14 signs/symptoms

PROTEIN INTERACTIONS: 1

1 associated gene
No signs/symptoms info

Hereditary thrombophilia due to congenital protein S deficiency

Mild hemophilia A


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	PROS1	(0.85)	F8

Citations in the biomedical literature:

Hereditary thrombophilia due to congenital protein S deficiency		Mild hemophilia A
	Synonym(s): (no synonyms)		Synonym(s): - Mild factor VIII deficiency

	Classification (Orphanet): (no data available)		Classification (Orphanet): - Rare genetic disease - Rare hematologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: x-linked recessive

	External references: 2 OMIM references - No MeSH references		External references: No OMIM references No MeSH references

Hereditary thrombophilia due to congenital protein S deficiency
	Very frequent - Autosomal dominant inheritance - Purpura / petichiae Frequent - Anomalies of skin, subcutaneous tissue and mucosae - Retinopathy - Skin hypoplasia / aplasia / atrophy - Thin skin - Venous thrombosis / phlebitis / thrombophlebitis Occasional - Abnormal pigmentary skin changes / skin pigmentation anomalies - Arterial embolism / thrombosis - Cerebral vascular anomalies - Chronic skin infection / ulcerations / ulcers / cancrum - Gangrena / necrosis - Pulmonary thromboembolism - Varices / varicous veins / venous insufficiency
Mild hemophilia A
(no data available)